Description
Product Characteristics:
Aliases: KIAA0526 antibody, LCB 2 antibody, LCB2 antibody, LCB2a antibody, Long chain base biosynthesis protein 2 antibody, Long chain base biosynthesis protein 2a antibody, Serine palmitoyl CoA transferase 2 antibody, Serine palmitoyltransferase 2 antibody, Serine palmitoyltransferase long chain base subunit 2 antibody, Serine palmitoyltransferase subunit II antibody, Serine-palmitoyl-CoA transferase 2 antibody, SPT 2 antibody, SPT2 antibody, SPTC2_HUMAN antibody, SPTLC 2 antibody, Sptlc2 antibody
Target Information: This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I. [provided by RefSeq, Mar 2011]